New DNA synthesizing technique can create genes overnight

In a recent study, a new DNA synthesizing method was developed, which has the ability to help biologists in creating much cheaper, faster, and easier synthetic DNA sequences.

A new gene creation process at the present is expensive and slower. The genetic code’s fundamental building blocks, bases are included one by one to a processing DNA strand. This entire process fails at times and tends to fall short of the juice just immediately after a sequence meets two hundred bases.

In the previously used method even if the rate of failure is known to be higher, it is regarded better for writing a lot of various small genetic codes and then combining all of them together by making use of enzymes. This new method indicated in the recent study is expected to remove much of the previous issues.

The method of DNA synthesizing used previously roots back to the year 1970. The method involves a slow process, which tends to make the genetic labs slow down even if the new technologies such as CRISPR help in speeding up the other sections of the process of gene-editing.

The new method discovered in this study performed lately at the Lawrence Berkeley National Laboratory would reportedly make a brute-force approach. In this process, the enzymes would physically bind every new DNA bit onto the sequence, prior to getting cut from the sequence. This process could continue up to eternity without stopping abruptly at two hundred bases.

As said by the researchers, this method tends to use lots of enzymes in the process. However, enzymes are not expensive. The researchers have strong belief that combining DNA sequences together by using the brute-force approach, would soon become a common practice in the genetics labs. Nevertheless, this new method has still not reached up to its highest speed and is prone to meet failure. The researchers, however, have said that they would make this new method much powerful so that soon complete artificial genes could be created overnight.

The findings of this new study were published in the Nature Biotechnology journal on Monday 18th June.

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